Take a direct flight, whenever possible. Nowadays, one in five planes does not arrive on time. While always frustrating, delays become real problems for connecting travelers who depend on a first flight’s prompt arrival in order to make the second leg. The advice, fly nonstop to the major airport nearest your destination, then drive the rest of the way.
Say you’re traveling from Denver to Ventura, California via Los Angeles International Airport, instead of taking a connecting flight from LAX to Oxnard Airport which is service to Ventura, you’ll save at least an hour off your travel time by hitting the highway, even with 75 minute drive. If you were going to rent a car anyway, you could save as much as $100.